Inside Neutrient Curcumin+

Curcumin is one of the most extensively researched phytonutrients in nutritional science, with thousands of preclinical studies and a growing number of human clinical trials exploring its anti-inflammatory and antioxidant properties. Derived from the rhizome of the turmeric plant, curcumin has been used in traditional Ayurvedic and Asian practices for centuries and continues to attract scientific interest for its potential role in supporting joint health, healthy ageing and overall wellbeing.

One of the main challenges with curcumin supplementation is that standard curcumin extracts are naturally difficult for the body to absorb. They are poorly soluble in water, rapidly metabolised and quickly eliminated, which means only a relatively small proportion may become available for use by the body.

Neutrient Curcumin+ has been formulated with this challenge in mind. It combines Theracurmin®, a patented Japanese colloidal dispersion technology shown to provide substantially greater bioavailability than standard curcumin extracts, with Casperome®, a phytosome-based boswellia extract designed to enhance the absorption of boswellic acids. Together, these patented ingredients provide a convenient, once-daily source of curcumin and boswellia in highly absorbable forms.

top 5 reasons to choose

Neutrient Curcumin+

Enhanced bioavailability

Theracurmin® has been shown in published pharmacokinetic studies to provide substantially greater curcumin absorption than standard extracts. Each 60mg capsule is equivalent in effective curcumin delivery to approximately 84g of turmeric root.

Dual-patented formula

Neutrient Curcumin+ combines Theracurmin® curcumin with Casperome® boswellia in a single once-daily capsule — two patented, clinically studied ingredients in one product.

Full-spectrum boswellia

Casperome® provides all 11 naturally occurring boswellic acids found in boswellia resin, rather than focusing on AKBA content alone.

Supported by a growing evidence base

Both Theracurmin® and Casperome® have been investigated in human clinical studies across a range of health areas, including joint comfort, cardiovascular and cognitive health.

Clean, vegan, once-daily

No colours, flavours, sweeteners, stimulants, lactose or unnecessary fillers. HPMC capsule shell suitable for vegans, two-year shelf life and simple once-daily dosing.

Theracurmin®: 42x more absorbable

A patented Japanese colloidal dispersion that reduces curcumin to sub-micron, water-dispersible particles — up to 42x more bioavailable than standard curcumin powder.

Casperome® phytosome boswellia

A phytosome-delivered boswellia extract combining boswellic acids with phospholipids for 3–7x higher plasma levels than standard boswellia.

Full-spectrum boswellia

All 11 naturally occurring boswellic acids, including beta-boswellic acid — not just standardised AKBA like many boswellia products.

Two complementary pathways

Curcumin targets NF-kB, COX-2 and iNOS; boswellic acids target the 5-LOX pathway — broader support for the body's natural inflammatory response than either alone.

What is curcumin? And what is boswellia?

People often ask whether curcumin and turmeric are the same thing. They are closely related but not identical: turmeric (Curcuma longa) is the whole plant root, while curcumin is the principal bioactive compound found within it, responsible for much of the root's vibrant yellow-orange colour. Turmeric belongs to the ginger family and is native to Southeast Asia, with India the world's largest producer. Around 20g of curcumin can be obtained from 1kg of turmeric root, though this varies with growing conditions.

Turmeric has a long history of use in traditional health practices across Asia, particularly in Ayurvedic traditions relating to digestive and inflammatory health. Traditional Indian recipes often combine turmeric with fats and black pepper — a pairing now understood to support curcumin absorption, given curcumin's fat solubility and the bioavailability-enhancing properties of piperine. Over recent decades, curcumin has become the subject of extensive laboratory and clinical research into its antioxidant, anti-inflammatory, neuroprotective and metabolic effects.

The composition of turmeric

Component	Detail
Curcuminoid content of turmeric	2–9% by weight
Curcumin (as % of curcuminoids)	~77%
Other curcuminoids	Demethoxycurcumin and bisdemethoxycurcumin make up the remainder
Curcumin yield	~20g per 1kg of turmeric root
In Neutrient Curcumin+	60mg curcumin per capsule as Theracurmin®

Why does bioavailability matter so much? Curcumin is naturally hydrophobic, meaning it does not dissolve easily in water. Because the digestive tract is largely water-based, a significant proportion of standard curcumin may pass through without being absorbed, while much of the absorbed fraction is rapidly metabolised by the liver and intestinal tissues. Improving bioavailability has therefore become a major focus of modern curcumin research — formulations such as Theracurmin® use colloidal dispersion technology to create very small, water-dispersible particles that may enhance absorption compared with standard extracts.

What is boswellia?

Boswellia serrata, commonly known as Indian frankincense, is a deciduous tree native to parts of India, North Africa and the Middle East. The resin from its bark has a long history of use in traditional Ayurvedic and Middle Eastern practices, particularly relating to joint and digestive wellbeing. Modern research has identified a group of compounds within the resin called boswellic acids, which have attracted interest for their potential role in supporting the body's normal inflammatory processes through mechanisms different from those of curcumin.

Boswellia resin naturally contains 11 different boswellic acids, including beta-boswellic acid (B-BA), acetyl-keto-beta-boswellic acid (AKBA) and acetyl-beta-boswellic acid (ABBA). Research suggests these may interact with the 5-lipoxygenase (5-LOX) pathway, involved in producing inflammatory signalling molecules called leukotrienes. Many boswellia extracts are standardised to AKBA content alone, whereas Casperome® is formulated to provide the full natural profile of all 11 boswellic acids, including beta-boswellic acid, which some research suggests may contribute significantly to boswellia's activity.

Food sources of curcumin and boswellia

While diet alone cannot deliver the concentrated amounts of curcumin and boswellic acids provided by Neutrient Curcumin+, the table below gives a sense of the natural sources. Boswellia resin is not a food ingredient, so dietary intake of boswellic acids is not practically achievable through food. Dietary curcumin from food also provides only trace amounts compared with supplemental forms, and is limited by the same absorption challenges that affect standard supplements.

Food source	Curcumin content	Boswellic acid content
Turmeric root (fresh)	~3% curcuminoids	~2–4% (as dried resin)
Turmeric powder (dried)	~2–9% curcuminoids	~3–8% (dried resin)
Curry powder	~0.3–3% curcuminoids	Trace amounts in spice blends
Golden milk / turmeric latte	Moderate (varies by recipe)	Not a significant source
Mustard (as colouring)	Very low (<0.1%)	Not a significant source
Frankincense / resin gum	Not applicable	Natural resin source

	Neutrient Curcumin+	Standard curcumin
Up to 42x more bioavailable (Theracurmin®)
Full-spectrum boswellia (Casperome®)
Dual anti-inflammatory pathways (NF-kB + 5-LOX)
Patented, clinically studied ingredients
Vegan, clean, once-daily capsule

Curcumin+ Benefits

Curcumin benefits: what the science says

Curcumin is one of the most extensively researched plant compounds, with studies exploring its effects across a wide range of body systems. While much of the evidence comes from laboratory and preclinical research, a growing number of human clinical studies have investigated its potential role in health and wellbeing. The sections below summarise the areas that have attracted the greatest scientific interest.

Curcumin benefits: what the science says

Inflammation and joint health

One of the most widely studied aspects of curcumin is its interaction with pathways involved in the body's natural inflammatory response. Research suggests it may influence NF-kB, a signalling molecule involved in regulating inflammatory cytokines, as well as COX-2 and lipoxygenase enzymes. These properties have made it a focus of research into conditions associated with long-term, low-grade inflammation, including those affecting joint comfort and mobility.

Arthritis

Curcumin has been widely studied for its potential role in supporting people with arthritis. A 2016 systematic review and meta-analysis in the Journal of Medicinal Food evaluated 29 randomised trials of turmeric extracts and curcumin in arthritis, concluding that curcumin may help support joint comfort and physical function, while noting that further high-quality studies are needed. A separate randomised, double-blind, placebo-controlled study in people with rheumatoid arthritis found 250mg or 500mg of curcumin twice daily over 90 days was associated with improvements in joint comfort and inflammation.

Antioxidant protection

Curcumin is recognised as a potent antioxidant and has been shown to interact with reactive oxygen and nitrogen species, produced naturally during metabolism and increased by factors such as pollution, UV exposure and inflammation. Research suggests it may also support the activity of the body's own antioxidant defence systems, including superoxide dismutase, catalase and glutathione. Laboratory studies have compared its antioxidant activity with that of vitamin E, though such findings cannot be directly translated to effects in humans.

Brain health and cognitive function

Curcumin has become an area of growing interest in neuroscience because of its antioxidant and anti-inflammatory properties, and advances in delivery technology have prompted research into whether enhanced-bioavailability forms may improve the amount available to the central nervous system. Preclinical studies have explored its interaction with amyloid-beta proteins, oxidative stress and neuroinflammatory pathways. In one randomised, double-blind, placebo-controlled study, a solid lipid curcumin formulation was associated with improvements in some measures of memory, attention, mood and fatigue in healthy older adults.

Mood and depression

Researchers have investigated curcumin for its potential role in mood and emotional wellbeing. Experimental studies suggest it may influence several biological pathways associated with mood regulation, including inflammatory signalling and neurotransmitter activity. A number of clinical studies have reported encouraging findings, leading researchers to suggest curcumin may have a role as a nutritional adjunct for some individuals, though more large-scale trials are needed before firm conclusions can be drawn.

Cardiovascular health

Curcumin has been studied for its potential effects on oxidative stress, lipid metabolism and vascular function. Research suggests it may help support healthy endothelial function and influence pathways involved in cholesterol homeostasis. Some studies have explored whether regular supplementation may contribute to improvements in measures of artery function, although further well-designed human trials are needed to confirm these observations.

Inflammatory bowel disease

Curcumin's antioxidant and anti-inflammatory properties have prompted research into its potential role in inflammatory bowel conditions such as ulcerative colitis and Crohn's disease. A systematic review and meta-analysis of seven randomised placebo-controlled trials reported positive findings when curcumin was used alongside standard care for ulcerative colitis. Research into Crohn's is more limited. Curcumin should be considered a nutritional supplement rather than a replacement for medical treatment.

Weight management and metabolic health

Research suggests curcumin may interact with biological pathways involved in metabolic health, including those associated with low-grade inflammation and fat-cell function. A preliminary study in overweight adults with metabolic syndrome reported greater reductions in body weight and measurements following curcumin supplementation alongside lifestyle changes, and a later meta-analysis of 21 studies found associations with improvements in body weight, BMI and waist circumference. A healthy diet and regular activity remain the cornerstones of long-term weight management.

Liver health

Curcumin has been investigated for its potential role in supporting normal liver function and metabolic health. Clinical research has explored its effects on markers associated with non-alcoholic fatty liver disease, with some studies reporting improvements in liver fat accumulation and blood markers. Laboratory and early human research has also examined its interaction with the metabolism of alcohol-derived compounds, though more research is required.

Healthy ageing

Oxidative stress and low-grade inflammation are thought to contribute to many of the biological changes associated with ageing. Because of its antioxidant and anti-inflammatory properties, curcumin has attracted interest as a nutritional ingredient that may help support healthy ageing. Laboratory and animal studies have explored its effects on cellular stress responses and age-related pathways, although human research in this area is still developing.

Why combine curcumin and boswellia?

Curcumin and boswellia have been studied for their potential to support the body's natural inflammatory response through different but complementary biological pathways. Research suggests curcumin may influence signalling pathways involving NF-kB, COX-2 and iNOS, while boswellic acids have been investigated primarily for their interaction with the 5-LOX pathway, which is involved in producing inflammatory signalling molecules called leukotrienes.

Because these pathways play different roles within the inflammatory response, combining curcumin and boswellia in a single formulation may provide broader nutritional support than either ingredient alone. In short, curcumin targets NF-kB inhibition, COX-2 suppression and iNOS inhibition, while boswellia targets 5-LOX inhibition and leukotriene-pathway modulation — two distinct routes to supporting the body's normal inflammatory processes.

"Curcumin is one of the best-researched botanical ingredients available, but the way it is formulated can make a significant difference to how much is absorbed. In practice, I often recommend enhanced-bioavailability curcumin alongside other dietary and lifestyle measures for clients looking to support joint comfort and overall wellbeing. The inclusion of Casperome® boswellia adds a complementary botanical ingredient with an interesting and growing evidence base."

Jacqueline Newson BSc (Hons) Nutritional Therapy — Nutritional Therapist

Six things worth knowing about curcumin

Curcumin comes from turmeric, but the two are not identical. Turmeric root typically contains around 2 to 9% curcuminoids by weight. A single capsule of Neutrient Curcumin+ provides 60mg of curcumin as Theracurmin®, a highly bioavailable form.

Curcumin has been the subject of thousands of scientific publications, making it one of the most widely researched plant compounds.

Traditional Indian cuisine often combines turmeric with fats and black pepper — ingredients now known to help support curcumin absorption.

Curcumin has demonstrated notable antioxidant activity in laboratory studies and has been compared with vitamin E in some experimental models.

In Japan, curcumin-containing beverages have become popular in relation to post-alcohol wellbeing, partly because of research exploring curcumin's interaction with acetaldehyde metabolism.

Some research suggests regular curcumin supplementation may support healthy vascular function, although more studies are needed.

What makes Neutrient Curcumin+ different?

Neutrient Curcumin+ has been formulated with two key considerations in mind. The first is that curcumin's naturally low bioavailability may limit the amount available to the body. The second is that combining highly absorbable forms of curcumin and boswellia may provide complementary nutritional support through different biological pathways. The table below shows how Theracurmin® compares with other curcumin forms on relative bioavailability.

Food source	Curcumin content	Boswellic acid content
Turmeric root (fresh)	~3% curcuminoids	~2–4% (as dried resin)
Turmeric powder (dried)	~2–9% curcuminoids	~3–8% (dried resin)
Curry powder	~0.3–3% curcuminoids	Trace amounts in spice blends
Golden milk / turmeric latte	Moderate (varies by recipe)	Not a significant source
Mustard (as colouring)	Very low (<0.1%)	Not a significant source
Frankincense / resin gum	Not applicable	Natural resin source

The bioavailability problem with standard curcumin

Standard curcumin extracts are naturally difficult to absorb because curcumin has very low water solubility. Studies suggest a large proportion of orally consumed curcumin may pass through the digestive tract without being absorbed, while much of the absorbed fraction is rapidly metabolised. This is one reason formulation technology has become an important area of curcumin research, focused on improving the amount available for absorption.

Theracurmin®: enhanced bioavailability

Theracurmin® is a patented Japanese curcumin formulation developed to improve the dispersion and absorption of curcumin. The technology reduces curcumin into sub-micron particles stabilised within a water-dispersible matrix, helping improve its availability in the digestive tract. Clinical pharmacokinetic studies have reported substantially higher absorption than standard unformulated powder, with published increases ranging from 27-fold to 42-fold depending on the comparator and methodology. It has been investigated in human studies exploring joint comfort, cardiovascular health and cognitive function.

Casperome®: phytosome-delivered boswellia

Casperome® is a patented boswellia extract that uses Phytosome® technology to support the absorption of boswellic acids, combining boswellia extract with phospholipids naturally found in cell membranes. Clinical research has reported higher circulating levels of boswellic acids following Casperome® supplementation compared with standard boswellia extracts. Unlike products focusing primarily on AKBA content, Casperome® is standardised to provide the full spectrum of naturally occurring boswellic acids found in the resin.

Why combine curcumin and boswellia?

Curcumin and boswellia have been studied for their interaction with different but complementary pathways in the body's natural inflammatory response. Curcumin has been investigated primarily in relation to NF-kB and COX-2, while boswellic acids have been studied for their interaction with 5-LOX. Because these pathways play different roles, combining the two in a single formulation may provide broader nutritional support than using either ingredient alone.

Clean formulation

Neutrient Curcumin+ contains no artificial colours, flavours, sweeteners or stimulants and is free from lactose and unnecessary fillers. The HPMC (hydroxypropyl methylcellulose) capsule shell is suitable for vegans, the product has a two-year shelf life and is supplied in recyclable packaging.

Ingredient	Amount per capsule	Role
Curcumin as Theracurmin®	60mg (equiv. to 84g turmeric root)	Patented Japanese colloidal dispersion of sub-micron, water-dispersible curcumin particles — up to 42x more bioavailable than standard curcumin. Studied for antioxidant properties and its potential role in joint, cognitive and metabolic health.
Boswellia serrata as Casperome®	250mg (equiv. to 500mg boswellia resin)	Phytosome-delivered full-spectrum boswellia providing all 11 boswellic acids including beta-boswellic acid — 3–7x higher plasma levels than standard boswellia. Studied for joint, digestive and respiratory wellbeing via 5-LOX pathways.
Lecithin (soy)	Excipient	Phospholipid carrier supporting the Phytosome® technology and capsule formulation; provides phosphatidylcholine as a cell-membrane building block.

Who is Neutrient Curcumin+ for?

Neutrient Curcumin+ is designed for adults looking for a high-quality curcumin and boswellia supplement with enhanced bioavailability. It may be particularly suitable for:

Individuals looking to support joint comfort and mobility as part of a healthy lifestyle

Active people and those with physically demanding lifestyles who want nutritional support for recovery and overall wellbeing

Older adults interested in maintaining mobility, cognitive health and healthy ageing

Those seeking a high-quality curcumin supplement that uses advanced absorption technology

Individuals interested in supporting metabolic, cardiovascular or digestive wellbeing as part of a balanced diet and healthy lifestyle

Anyone wishing to incorporate well-researched botanical ingredients into their daily wellness routine

How to take Neutrient Curcumin+

Take 1 capsule daily, providing 60mg of curcumin as Theracurmin® and 250mg of boswellia as Casperome®. The enhanced-bioavailability forms mean a single, modest-dose capsule is designed to deliver more than much larger doses of standard extracts.

With or after food

Curcumin is fat-soluble, so taking the capsule with a meal containing some fat may further support absorption and comfortable digestion

Consistency matters

Botanical ingredients are generally studied with regular, ongoing use. Taking Curcumin+ daily over a sustained period is more in keeping with how it has been researched than occasional use

Any time of day

There is no required time of day. Choose a moment that fits your routine and is easy to remember, such as with breakfast or your main meal

Storage

Store in a cool, dry place away from direct sunlight. Use within 6 months of opening. The product has a two-year shelf life and recyclable packaging

How safe is Curcumin+?

Curcumin has been widely studied and is generally considered well tolerated when used at appropriate doses. Human studies have investigated doses considerably higher than those found in Neutrient Curcumin+, which provides 60mg of curcumin as Theracurmin® together with 250mg of boswellia as Casperome®, using enhanced-bioavailability forms developed to improve absorption.

As with any food supplement, individuals taking medication or living with an existing medical condition should seek advice from a healthcare professional before use. Curcumin may interact with anticoagulant medication and may not be suitable for some individuals without professional guidance.

Curcumin+ is not recommended for children under 18 years of age, or during pregnancy or breastfeeding. Store in a cool, dry place away from direct sunlight and use within 6 months of opening.

Disclaimer

Caution: not recommended for people taking anticoagulants, children under 18, or pregnant or breastfeeding women. Consult a healthcare professional before use if you are taking medication or have a medical condition. Food supplements are not a substitute for a varied and balanced diet and a healthy lifestyle. Store in a cool, dry place away from direct sunlight. Use within 6 months of opening.

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