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Inside Neutrient Multi+

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Multi+

Your complete guide to a high-specification multivitamin — 24 nutrients, active forms, chelated minerals, and the science behind every decision.

Most people know they should probably take a multivitamin. Far fewer know whether the one they are taking is actually doing anything. Shelves and websites are filled with multivitamin tablets that list impressive numbers of nutrients but say nothing about the forms those nutrients are in, the doses that matter, or whether any thought has been given to how they interact.

The uncomfortable truth is that most multivitamins are built around one constraint: cost. That means synthetic B vitamins that require conversion steps many people cannot perform efficiently, mineral forms with poor absorption, and formulas that hit regulatory checkboxes without asking what optimal nutrition actually looks like.

Neutrient Multi+ was designed from a different starting point. Rather than working from the RDA — a threshold set to prevent deficiency — it was formulated around the question of what genuine nutritional support requires: methylated B vitamins in active forms, chelated minerals with documented bioavailability advantages, rare trace elements including boron and molybdenum, iodine from whole bladderwrack extract, and PQQ at a proper clinical dose to support cellular energy. It represents a genuinely modern approach to daily micronutrient support.

top 5 reasons to choose

Neutrient Multi+

Clinical-quality nutrient forms

Active methylated B vitamins (5-MTHF folate, methylcobalamin B12, riboflavin-5-phosphate), chelated minerals (bisglycinate zinc and iron, citrate magnesium) and the natural d-alpha form of vitamin E are selected to support nutrient availability and utilisation.

24 active nutrients, including novel ingredients

The inclusion of PQQ at 20mg and myo-inositol reflects a formulation informed by emerging nutritional research rather than conventional multivitamin design.

Intelligent formulation

Deliberate nutrient pairings, active forms, chelated minerals, whole-plant iodine and the considered exclusion of calcium and vitamin C reflect a carefully constructed formula.

Gluten-free, animal-derivative-free, filler-free

A clean formulation with no unnecessary excipients, in a compact capsule format suitable for daily use.

Two months' supply per bottle

120 capsules providing a two-month supply at the recommended 2 capsules per day — good value for a formula of this specification.

Neutrient®
Methylated & active B vitamins
Chelated minerals
PQQ 20mg
Specialist trace elements

Methylated B vitamins throughout

5-MTHF folate and methylcobalamin B12 in active forms that work regardless of MTHFR gene status, alongside riboflavin-5-phosphate, pyridoxine-5-phosphate and D-biotin.

Chelated, bioavailable minerals

Zinc bisglycinate, ferrous bisglycinate and buffered magnesium citrate for superior absorption and gastrointestinal tolerance compared with cheap oxides and sulphates.

PQQ at a therapeutic dose

20mg of pyrroloquinoline quinone per serving, a level consistent with published human studies, to support mitochondrial biogenesis and cellular energy.

Boron, molybdenum & kelp iodine

Rare trace elements most formulas leave out, plus natural Fucus vesiculosus iodine and myo-inositol — with vitamin C and calcium intentionally excluded for precise tailoring.

Methylated B vitamins throughout

5-MTHF folate and methylcobalamin B12 in active forms that work regardless of MTHFR gene status, alongside riboflavin-5-phosphate, pyridoxine-5-phosphate and D-biotin.

Chelated, bioavailable minerals

Zinc bisglycinate, ferrous bisglycinate and buffered magnesium citrate for superior absorption and gastrointestinal tolerance compared with cheap oxides and sulphates.

PQQ at a therapeutic dose

20mg of pyrroloquinoline quinone per serving, a level consistent with published human studies, to support mitochondrial biogenesis and cellular energy.

Boron, molybdenum & kelp iodine

Rare trace elements most formulas leave out, plus natural Fucus vesiculosus iodine and myo-inositol — with vitamin C and calcium intentionally excluded for precise tailoring.

Neutrient®

What is Neutrient Multi+?

Multi+ is a comprehensive multivitamin and mineral formula containing 24 nutrients across vitamins, minerals and specialist compounds. It is designed for adults who want meaningful nutritional coverage rather than a token supplement.

What distinguishes it from standard multivitamins is not simply the number of ingredients but the form of every ingredient. Each nutrient is selected for bioavailability — the degree to which it can actually be absorbed and used by the body. A supplement can appear impressive on its label while delivering very little in practice if the forms used are poorly absorbed or biologically inactive.

Even with the best intentions, achieving a perfectly balanced, nutrient-rich diet every single day is challenging. Soil nutrient depletion, food processing, chronic stress and irregular eating patterns all contribute to potential shortfalls, often leaving subtle gaps that can affect energy, mood and resilience. Research confirms that micronutrient insufficiencies are common even in populations with widespread food access, and that many diets considered healthy may still leave significant gaps. In older adults, a daily multivitamin is an effective way to improve levels of nutrients such as vitamin D, B6, B12, folate, iodine and selenium, which are frequently suboptimal due to reduced absorption and narrower dietary variety. A supplement cannot replace a varied whole-food diet — but for the realistic majority whose diet, lifestyle or absorption is not always perfect, it provides a reliable nutritional foundation.

What Multi+ does and does not contain

Category What Neutrient Multi+ provides
Fat-soluble vitamins Vitamins A (retinyl acetate), D3 (cholecalciferol), E (natural d-alpha tocopheryl succinate) and K2 (MK-4)
B vitamin complex All eight B vitamins in active coenzyme forms
Essential minerals Magnesium, zinc, iron, selenium, copper, manganese, chromium and iodine
Rare trace minerals Boron (disodium tetraborate) and molybdenum (sodium molybdate)
Phospholipid precursor Myo-inositol for cell membrane and neurological support
Mitochondrial support PQQ (pyrroloquinoline quinone) at 20mg per serving
Intentionally excluded No vitamin C or calcium, and no fillers, artificial colours, flavourings, sweeteners or unnecessary binders
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Food sources of key nutrients

A well-formulated supplement works alongside food, not instead of it. Understanding which foods are richest in key nutrients helps explain why gaps are common even in people eating varied, balanced diets.

Nutrient Richest food sources Why supplementation adds value
Vitamin D3 Oily fish, egg yolk, beef liver UVB synthesis is blocked by glass, sunscreen and cloud, and is negligible in the UK Oct–Apr. Low status remains common.
Vitamin B12 Meat, fish, shellfish, dairy, eggs Absent from plant foods; absorption declines with age, low stomach acid and long-term PPI or metformin use.
Folate (B9 as 5-MTHF) Liver, spinach, kale, legumes Heat-sensitive and reduced by storage and cooking; active 5-MTHF is of particular interest for common MTHFR variants.
Magnesium Pumpkin seeds, dark chocolate, almonds, spinach Stripped by food processing and reduced by soil depletion; many adults do not meet recommended intakes.
Iodine Seaweed, white fish, dairy, eggs Plant-based diets are frequently deficient and UK dairy iodine has fallen; kelp-derived iodine is a natural, reliable source.
Zinc Oysters, red meat, crab, pumpkin seeds Phytates in wholegrains and legumes can reduce absorption by up to 50% from plant sources.
PQQ Fermented soy (natto), green tea, parsley Dietary intake is typically under 1mg/day; clinical doses (10–20mg) are far higher than food provides.
Boron Raisins, almonds, avocado, prunes Intake may be low in diets limited in fruit, nuts and vegetables; boron supports bone and mineral metabolism.

What makes Neutrient Multi+ different from other multivitamins?

Neutrient Multi+Standard multivitamins
High doses that make a difference
Methylated B-vitamins (5-MTHF, Methylcobalamin) instead of synthetic folic acid or cyanocobalamin
Chelated bisglycinate minerals, not oxides or sulphates
Natural d-alpha tocopherol vitamin E, not synthetic dl-alpha
Includes trace minerals such as boron, molybdenum + kelp iodine
A notable dose of PQQ - 20mg

What is Neutrient Multi+ good for?

The 24 nutrients in Neutrient Multi+ work across multiple body systems at once through the combined actions of their individual nutrients. The sections below describe some of the key health areas the formula is designed to support.

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The many benefits of Neutrient Multi+, supported by clinical research

Nervous system and psychological function

B vitamins and magnesium contribute to normal nervous system function, while zinc contributes to normal cognitive function. B1, B3, B6, B12 and biotin contribute to normal psychological function, supporting mental clarity, focus and mood as part of everyday nutritional maintenance. Myo-inositol is a phospholipid precursor involved in serotonin and dopamine receptor signalling, with clinical evidence in mood and anxiety.

Energy metabolism

The B vitamins — thiamin, riboflavin, niacin, pantothenic acid, B6 and B12 — contribute to normal energy metabolism by supporting the enzymatic reactions that convert carbohydrates, fats and proteins into ATP. Iron supports normal oxygen transport and helps reduce tiredness and fatigue, while iodine and magnesium further support energy metabolism. PQQ at 20mg supports mitochondrial biogenesis — the formation of new mitochondria — through a mechanism distinct from the B vitamins.

Immune function

Vitamins A, D3, zinc, selenium and copper each play distinct, well-documented roles in immune function. Vitamin D3 is recognised for its involvement in immune cell signalling as well as calcium absorption, and zinc contributes to the normal development and function of immune cells, with inadequate status impairing normal immune responses.

Bone health

Bone health depends on far more than calcium alone. Vitamin D3 contributes to normal calcium absorption and utilisation, vitamin K2 as MK-4 activates proteins involved in bone metabolism, and magnesium is required for vitamin D metabolism and the maintenance of normal bones, while boron plays a supportive role. Multi+ provides 20mcg (800 IU) of D3 — 400% of the NRV — per daily serving.

Thyroid function

Multi+ provides iodine from Fucus vesiculosus (bladderwrack kelp), a natural marine source that also supplies trace minerals. Selenium, as L-selenomethionine, contributes to normal thyroid function and supports enzymes involved in thyroid hormone metabolism, including the conversion of T4 to the more active T3. Together these nutrients support normal thyroid hormone production.

Fertility and reproductive health

Several nutrients are relevant to reproductive health in both men and women. Vitamin B6 contributes to the regulation of hormonal activity; folate and B12 contribute to normal cell division and red blood cell formation; zinc contributes to normal fertility and reproduction; and selenium contributes to normal spermatogenesis. Myo-inositol is an emerging area of interest in women's health and fertility research.

Skin, hair and vision

Vitamin A and biotin contribute to the maintenance of normal skin, biotin supports normal hair, vitamin A contributes to normal vision, and riboflavin contributes to the maintenance of normal mucous membranes. Together these nutrients address the nutritional foundations of appearance from within.

Antioxidant protection

Vitamins A and E, together with zinc, selenium and copper, contribute to the protection of cells from oxidative stress. Selenium is a cofactor for glutathione peroxidase, one of the body's key antioxidant enzymes, and natural d-alpha vitamin E helps protect cell membranes from oxidative damage. PQQ has attracted scientific interest for its redox activity and potential role in cellular antioxidant pathways.

Neutrient®

Why form matters: bioavailability

Bioavailability describes how much of a nutrient your body can actually absorb and use after taking it. A supplement can show high amounts on its label yet deliver far less if the forms used are poorly absorbed or require conversion steps that many people cannot complete efficiently. This is the central limitation of most standard multivitamins: cheaper synthetic forms reduce manufacturing costs but substantially reduce the benefit to the person taking the product.

The B vitamin family plays a central role in energy metabolism, nervous system function and cell production, yet many formulas use precursor forms that must first be converted into their active forms. Common variations in the MTHFR enzyme are widespread and may reduce how efficiently some individuals convert folic acid into active methylfolate (5-MTHF). Multi+ therefore uses methylfolate rather than folic acid, methylcobalamin rather than cyanocobalamin, and riboflavin-5-phosphate rather than standard riboflavin.

Minerals follow the same principle. Amino acid chelates and organic acid complexes — zinc and iron bisglycinate, buffered magnesium citrate, L-selenomethionine — offer advantages in bioavailability, tolerability or stability compared with inorganic oxides and sulphates.

"The RDA was designed to prevent deficiency, not to help you thrive. When I formulated Multi+, I started from a different question: what do optimal levels actually look like? That's why it contains methylated B vitamins, rare trace minerals like boron and molybdenum, and PQQ at a proper dose. Most supplements cut corners on the ingredients that matter most. We didn't."
Jonathan Orchard BSc (Hons) MBAcC
Jonathan Orchard BSc (Hons) MBAcC
Neutrient™ Founder

Six things worth knowing about Neutrient Multi+

MTHFR variations are more common than many realise. Common variations in the MTHFR gene are widespread and may reduce how efficiently some people convert folic acid into active methylfolate. Multi+ provides folate as 5-MTHF together with methylcobalamin, the active form of B12.

Reference values prevent deficiency, not optimise health. NRVs are set to prevent deficiency in most healthy people. They do not reflect the levels used in research on performance, healthy ageing or long-term wellbeing. Multi+ is formulated using both established requirements and contemporary research.

PQQ has attracted attention for mitochondrial health. Unlike most antioxidants, PQQ has been investigated for its potential role in mitochondrial biogenesis — the formation of new mitochondria. Multi+ provides 20mg per serving, consistent with amounts used in published human studies.

K2 (MK-4) and D3 have complementary roles. Vitamin D3 contributes to normal calcium absorption, while vitamin K contributes to the maintenance of normal bones by activating vitamin K-dependent proteins. Multi+ includes both as part of a comprehensive approach to bone health.

Fucus vesiculosus iodine is not the same as potassium iodide. Bladderwrack kelp is a natural marine source of iodine that also provides supporting trace minerals — the form most consistent with traditional dietary iodine from seafood.

Vitamin C and calcium are excluded by design. Requirements for both vary considerably with diet, life stage and individual goals. Excluding them lets practitioners and users tailor supplementation more precisely.

What makes Neutrient Multi+ different?

The multivitamin market is crowded, and the difference between products is rarely visible on the front of a pack. The decisions below distinguish Neutrient Multi+ from conventional multivitamin tablets. It starts with the B vitamins: where most formulas use precursor forms that require conversion, Multi+ uses active, coenzyme forms throughout.

The intentional exclusions: vitamin C and calcium

Multi+ does not include vitamin C or calcium, reflecting a flexible formulation approach. Vitamin C requirements vary widely and supplemental intakes often exceed the levels typically found in multivitamins, so excluding it lets users tailor intake precisely. Calcium requirements differ by diet, life stage and health status; Multi+ supplies the supporting nutrients D3 and K2 so calcium can be adjusted separately where needed.

Active, methylated B vitamins throughout

Multi+ provides B vitamins in coenzyme or biologically active forms where appropriate. The clearest example is folate: synthetic folic acid requires enzymatic conversion to 5-MTHF via the MTHFR enzyme, and common genetic variants may influence that conversion. Multi+ uses L-5-methyltetrahydrofolate calcium, a bioactive folate that participates directly in methylation, with B12 as methylcobalamin and B2 and B6 in their phosphorylated coenzyme forms.

Nutrient Form Per 2-capsule serving Primary function
Vitamin B1 Thiamine HCl 50mg Carbohydrate energy metabolism; nerve function
Vitamin B2 Riboflavin-5-phosphate 50mg Energy metabolism; FAD/FMN coenzymes
Vitamin B3 Nicotinamide 108mg NAD+ synthesis; energy metabolism; DNA repair
Vitamin B5 D-calcium pantothenate 18mg Coenzyme A synthesis; energy metabolism
Vitamin B6 Pyridoxine-5-phosphate 7mg Neurotransmitter synthesis; methylation
Vitamin B7 D-biotin 900mcg Fatty acid synthesis; hair & skin structure
Vitamin B9 L-methylfolate calcium 360mcg DNA synthesis; cell division; methylation
Vitamin B12 Methylcobalamin 50mcg Nerve health; red blood cell formation
Chelated and bioavailable minerals

Minerals are provided in forms selected for solubility and bioavailability. Zinc bisglycinate and ferrous bisglycinate offer favourable absorption and gastrointestinal tolerance compared with inorganic oxides and sulphates. Magnesium is provided as buffered citrate, a well-studied oral form, and selenium as L-selenomethionine, an organic form efficiently incorporated into body proteins.

Nutrient Form Per 2-capsule serving Primary function
Zinc Bisglycinate 13mg elemental Immunity; wound healing; antioxidant enzymes
Iron Ferrous bisglycinate 10mg elemental Oxygen transport; energy; cognitive function
Specialist trace elements: boron, molybdenum and kelp iodine

These trace elements are uncommon in standard formulas but have recognised roles. Boron (from disodium tetraborate) contributes to bone metabolism and may influence steroid hormone balance. Molybdenum (sodium molybdate) is a cofactor for enzymes such as sulphite oxidase. Iodine from Fucus vesiculosus is a natural kelp source that also provides additional trace minerals absent from synthetic iodide.

Nutrient Form Per 2-capsule serving Primary function
Boron Disodium tetraborate 1mg elemental Bone health; steroid hormone balance
Molybdenum Sodium molybdate 160mcg elemental Sulphite oxidase cofactor; sulphite metabolism
Iodine Fucus vesiculosus 300mcg elemental Thyroid hormone synthesis; normal thyroid function
PQQ: mitochondrial support at a studied dose

PQQ is a naturally occurring redox-active compound found in small amounts in certain foods. It is not a vitamin but behaves like one, and is notable for redox cycling — it can react and then revert to an active form, a rechargeable quality that distinguishes it from conventional antioxidants. Research is exploring its role in mitochondrial biogenesis, cognitive function and metabolic support. Multi+ provides 20mg per serving, consistent with doses used in clinical research.

Nutrient Form Per 2-capsule serving Primary function
PQQ Pyrroloquinoline quinone 20mg Mitochondrial function; antioxidant activity
D3 and K2-MK4: the calcium partnership

Vitamin D3 contributes to normal calcium absorption and utilisation, while vitamin K2 (as MK-4) is involved in activating vitamin K-dependent proteins such as osteocalcin and matrix Gla-protein, which play roles in bone mineralisation and calcium handling. Adequate vitamin K status may help support normal calcium distribution alongside vitamin D, particularly for bone and cardiovascular health.

Nutrient Form Per 2-capsule serving Primary function
Vitamin D3 Cholecalciferol 800 IU (20mcg) Calcium absorption; immune function; mood
Vitamin K2 Menaquinone-4 (MK-4) 50mcg Blood clotting; activation of osteocalcin and MGP
Myo-inositol

Myo-inositol is a naturally occurring carbohydrate compound that forms part of cell membranes and plays a role in cellular signalling. It is the most abundant form of inositol in the body and is the subject of active research, particularly in women's health and fertility, where it has been studied in relation to hormonal balance and ovarian function. Multi+ provides 100mg per serving.

Nutrient Form Per 2-capsule serving Primary function
Myo-inositol Myo-inositol 103mg Cell membrane structure; serotonin/dopamine signalling
Other essential vitamins + minerals
Nutrient Form Per 2-capsule serving Primary function
Vitamin A Retinyl acetate 1.2mg (3,490 IU) Vision; immune cell differentiation; skin renewal
Vitamin E D-alpha tocopheryl succinate 50mg Antioxidant protection; membrane integrity
Manganese Gluconate 1mg elemental Antioxidant cofactor (MnSOD); bone matrix
Copper Gluconate 2mg elemental Iron metabolism; connective tissue; nerve function
Selenium L-selenomethionine 90mcg elemental Antioxidant defence; T4→T3 thyroid conversion
Magnesium Citrate (buffered) 160mg elemental 300+ enzymatic reactions; energy; muscle & nerve
Chromium Picolinate 120mcg elemental Blood glucose regulation; macronutrient metabolism
Neutrient®

Who is Neutrient Multi+ for?

Neutrient Multi+ is designed as an intelligent daily nutritional foundation for anyone who recognises that their diet, however good, may not consistently deliver optimal levels of every essential micronutrient. It may be particularly suitable for:

• People with common MTHFR gene variants who may prefer methylated folate and B12 rather than folic acid and cyanocobalamin

• Adults looking to support energy metabolism through active B vitamins and emerging ingredients such as PQQ

• Those focused on bone health, particularly post-menopausal women wanting D3, K2, magnesium and boron in one formula

• People following plant-based or dairy-free diets, who may have lower intakes of B12, iodine, iron and zinc

• Women seeking a comprehensive multivitamin with active folate, iron, iodine and myo-inositol relevant to energy, reproductive health and hormonal function

• Men seeking broad-spectrum support including zinc, selenium and B vitamins for reproductive health, cognition and energy

• Adults in midlife and beyond wanting nutrients relevant to bone health, thyroid function and healthy ageing

• Health-conscious individuals who value transparency around nutrient forms, dosages and formulation decisions

Neutrient®

How to take Neutrient Multi+

The recommended daily serving is 2 capsules, taken with the first meal of the day. The fat-soluble vitamins (A, D3, E and K2) absorb significantly better when consumed alongside dietary fat. Each bottle of 120 capsules provides a two-month supply.

Pre- or post-workout

Taking Multi+ around exercise supports the elevated demand on B vitamins, magnesium and minerals during and after physical activity

Consistency matters

Daily supplementation over 8–12 weeks typically shows the greatest measurable impact on nutrient status, particularly for B12, folate and fat-soluble vitamins. Short-term use may not adequately replenish depleted stores

Avoid with medications

Avoid taking within two hours of pharmaceutical medications unless directed by your practitioner. Minerals including iron and zinc can interfere with the absorption of some drugs

With water

Take with a full glass of water to support capsule dissolution and gastric absorption

Neutrient®

Is Neutrient Multi+ safe?

Neutrient Multi+ is formulated with safety as well as efficacy in mind, with doses that reflect current nutritional science rather than maximising label numbers. A few considerations are worth noting:

Vitamin A: Multi+ provides 1.2mg (3,490 IU). High supplemental intakes of preformed vitamin A should be avoided during pregnancy except under medical supervision.

Vitamin K and anticoagulants: Vitamin K may affect the action of anticoagulant medications such as warfarin. Those taking blood-thinning medication should consult their healthcare provider before use.

Iron: Multi+ provides 10mg of iron per serving. Although below established upper safe intakes, iron supplementation is not necessary for everyone; those with conditions affecting iron metabolism should seek guidance first.

Thyroid conditions: Individuals with diagnosed thyroid disorders or taking thyroid medication should consult their provider before taking a supplement containing iodine.

Disclaimer

For adult use only. Food supplements are not a substitute for a varied diet and a healthy lifestyle. Always consult a medical professional before starting a new supplement routine if you are pregnant, breastfeeding, trying to conceive, taking medication or managing a medical condition. Do not exceed the stated recommended daily intake. Keep out of the reach of children.

References

1. Kennedy DO. B vitamins and the brain: mechanisms, dose and efficacy. Nutrients. 2016;8(2):68.

2. Obeid R, et al. Cobalamin coenzyme forms vs cyano- and hydroxyl-cobalamin: plasma levels and homocysteine. Am J Clin Nutr. 2015;101(4):784-9.

3. Stover PJ. Physiology of folate and vitamin B12 in health and disease. Nutr Rev. 2004;62(6):S3-12.

4. Hartle JW, et al. Comparative absorption of magnesium from five magnesium sources. J Nutr. 2016;22(11):1161-6.

5. Wegmüller R, et al. Zinc absorption from supplemental zinc citrate comparable to zinc gluconate. J Nutr. 2014;144(2):132-6.

6. Geleijnse JM, et al. Dietary intake of menaquinone and risk of coronary heart disease. J Nutr. 2004;134(11):3100-5.

7. Zimmermann MB, Boelaert K. Iodine deficiency and thyroid disorders. Lancet Diabetes Endocrinol. 2015;3(4):286-295.

8. Harris CB, et al. Dietary PQQ alters indicators of inflammation and mitochondrial metabolism. J Nutr Biochem. 2013;24(12):2076-84.

9. Bolland MJ, et al. Calcium supplements with or without vitamin D and cardiovascular risk. BMJ. 2011;342:d2040.

10. Stover PJ. Physiology of folate and vitamin B12. Nutr Rev. 2004;62(6):S3-12.

11. Unfer V, et al. Myo-inositol effects in women with PCOS: a meta-analysis. Gynecol Endocrinol. 2012;28(12):969-74.

12. Depeint F, et al. Mitochondrial function and toxicity: role of B vitamins. Chem Biol Interact. 2006;163(1-2):113-32.

13. Aranow C. Vitamin D and the immune system. J Investig Med. 2011;59(6):881-6.

14. Prasad AS. Zinc in human health: effect on immune cells. Mol Med. 2008;14(5-6):353-57.

15. Uwitonze AM, Razzaque MS. Role of magnesium in vitamin D activation. J Am Osteopath Assoc. 2018;118(3):181-189.

16. Nielsen FH. Update on human health effects of boron. J Trace Elem Med Biol. 2014;28(4):383-7.

17. Schomburg L. Dietary selenium and human health. Nutrients. 2017;9(1):22.

18. Frosst P, et al. A common mutation in methylenetetrahydrofolate reductase. Nat Genet. 1995;10(1):111-3.

19. Bailey SW, Ayling JE. Extremely slow activity of dihydrofolate reductase in human liver. PNAS. 2009;106(36):15424-9.

20. Greenberg JA, Bell SJ, Ausdal WV. Folic acid supplementation and pregnancy. Rev Obstet Gynecol. 2011;4(2):52-59.

21. Carmel R. Cobalamin deficiency. In: Homocysteine in Health and Disease. Cambridge University Press. 2001.

22. Roth-Maier DA, et al. Bioavailability of riboflavin. Int J Vitam Nutr Res. 2002;72(5):316-321.

23. Clayton PT. B6-responsive disorders. J Inherit Metab Dis. 2006;29(2-3):317-326.

24. Schuette SA, Lashner BA, Janghorbani M. Bioavailability of magnesium diglycinate vs magnesium oxide. JPEN. 1994;18(5):430-5.

25. Wegmüller R, et al. Zinc absorption from bisglycinate. J Nutr. 2014;144(2):132-6.

26. Szarfarc SC, et al. Iron bis-glycinate chelate vs ferrous sulfate. Arch Latinoam Nutr. 2001;51(1 Suppl 1):42-7.

27. Combs GF Jr. Selenium in global food systems. Br J Nutr. 2001;85(5):517-47.

28. Teng X, et al. Fucus vesiculosus as iodine source: a systematic review. Thyroid. 2006;16(5):455-460.

29. Grant KE, et al. Chromium and exercise training. Med Sci Sports Exerc. 1997;29(8):992-8.

30. Holick MF. Vitamin D deficiency. N Engl J Med. 2007;357(3):266-281.

31. Gregory JF. Nutritional properties of vitamin glycosides. Annu Rev Nutr. 1998;18:277-296.

32. Workinger JL, Doyle RP, Borber J. Challenges in diagnosis of magnesium status. Nutrients. 2018;10(9):1202.

33. Rayman MP. The importance of selenium to human health. Lancet. 2000;356(9225):233-241.

34. Lonnerdal B. Dietary factors influencing zinc absorption. J Nutr. 2000;130(5):1378S-1383S.

35. Rucker R, et al. Biochemistry and physiology of PQQ. J Nutr Biochem. 2009;20(1):1-9.

36. Turnlund JR, et al. Molybdenum absorption and retention studied with stable isotopes. Am J Clin Nutr. 1995;62(4):790-6.

37. Nakano M, et al. Effects of PQQ disodium salt on cognitive function. Food Funct. 2016;7(7):2988-2995.

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